近期大量上市！医生提醒→
<p style="line-height: 2em;margin-bottom: 0px;visibility: visible;margin-top: 0px;" data-pm-slice="0 0 []"><span leaf="" style="visibility: visible;"><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">眼下柚类水果大量上市，酸甜多汁的“柚味”很多人喜欢。目前市面上售卖的带“柚”字的水果有很多种，沙田柚、青柚、红蜜柚、文旦柚、胡柚、葡萄柚、西柚……</span></span></p><p style="line-height: 2em;margin-bottom: 0px;visibility: visible;margin-top: 0px;" data-pm-slice="0 0 []"><span leaf="" style="visibility: visible;"><br/></span></p><p><br/></p><section style="text-align: center;line-height: 2em;margin-bottom: 0px;visibility: visible;margin-top: 0px;" nodeleaf=""></section><p><br/></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><br/></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">需要注意的是：在服用某些药物时同时吃“柚味”，药效可能“失控”，甚至带来健康风险。</span></span></p><p><br/></p><section data-role="title" data-tools="135编辑器" data-id="164716" data-pm-slice="0 0 []"><section style="margin: 10px auto;display: flex;justify-content: center;"><section><section style="display: flex;justify-content: flex-end;height: 0px;transform: rotateZ(0deg);line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><br/></span></section><section style="display: flex;margin: 0 15px;"><section style="flex-shrink: 0;display: flex;align-items: flex-end;"><section style="width: 6px;height: 80%;border-left: 1px solid rgb(21, 84, 162);border-bottom: 1px solid rgb(21, 84, 162);border-top: 1px solid rgb(21, 84, 162);box-sizing: border-box;line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><br/></span></section></section><section style="width: 100%;max-width:100% !important;box-sizing:border-box;" data-width="100%"><section style="background-color: #faf7ef;padding: 6px 20px;box-sizing:border-box;"><section style="font-size: 18px;color: rgb(21, 84, 162);text-align: center;line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><strong data-brushtype="text"><span leaf=""><span textstyle="" style="font-size: 16px; letter-spacing: 2px;">吃“柚”要注意</span></span></strong><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">这些事</span></span></section></section><section style="height: 6px;width: 97%;border-right: 1px solid rgb(21, 84, 162);border-bottom: 1px solid rgb(21, 84, 162);box-sizing: border-box;line-height: 2em;margin-bottom: 0px;margin-top: 0px;" data-width="97%"><span leaf=""><br/></span></section></section></section></section></section></section><p><br/></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">柚子，尤其是西柚中</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">含有</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">呋喃香豆素类物质，这种成分会抑制肝脏里一种酶</span><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">（一种名为CYP3A4的药物代谢酶，小肠黏膜中也有）。而我们</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">吃的很多药物，都需要靠这种酶来代谢分解——酶被抑制后</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">，药物没法正常“消化”，就会在血液里越积越多，</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">相当于“过量服药”</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">，副作用风险自然大幅升高。</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">需要注意的是：</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">对药物代谢影响最明确、证据最充分的是“西柚/葡萄柚”</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">，而不是我们中秋常见的“柚子/蜜柚/文旦/沙田柚”。</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><br/></span></p><p><br/></p><section style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;" nodeleaf=""></section><p><br/></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><br/></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">正确吃柚子，首先我们要注意：</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">1、看清名称：</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">写“西柚/葡萄柚”或“grapefruit juice”的药品说明书，务必严格回避；“柚子/蜜柚”不是“西柚”。</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">2、拿不准就当“西柚”处理：</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">市场上部分果汁/饮料标注不清，若无法确认，按“西柚”口径避开更安全。</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">3、服药期间更要谨慎：</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">西柚的影响可持续24–72小时，错开几小时未必能完全避免相互作用。</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><br/></span></p><p><br/></p><section data-role="title" data-tools="135编辑器" data-id="164716" data-pm-slice="0 0 []"><section style="margin: 10px auto;display: flex;justify-content: center;"><section><section style="display: flex;justify-content: flex-end;height: 0px;transform: rotateZ(0deg);line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><br/></span></section><section style="display: flex;margin: 0 15px;"><section style="flex-shrink: 0;display: flex;align-items: flex-end;"><section style="width: 6px;height: 80%;border-left: 1px solid rgb(21, 84, 162);border-bottom: 1px solid rgb(21, 84, 162);border-top: 1px solid rgb(21, 84, 162);box-sizing: border-box;line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><br/></span></section></section><section style="width: 100%;max-width:100% !important;box-sizing:border-box;" data-width="100%"><section style="background-color: #faf7ef;padding: 6px 20px;box-sizing:border-box;"><section style="font-size: 18px;color: rgb(21, 84, 162);text-align: center;line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><strong data-brushtype="text"><span leaf="" data-pm-slice="1 1 "><span textstyle="" style="font-size: 16px; letter-spacing: 2px;">这几类药</span></span></strong></section><section style="font-size: 18px;color: rgb(21, 84, 162);text-align: center;line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><strong data-brushtype="text"><span leaf="" data-pm-slice="1 1 "><span textstyle="" style="font-size: 16px; letter-spacing: 2px;">千万别和“西柚/葡萄柚”一起吃</span></span></strong></section></section><section style="height: 6px;width: 97%;border-right: 1px solid rgb(21, 84, 162);border-bottom: 1px solid rgb(21, 84, 162);box-sizing: border-box;line-height: 2em;margin-bottom: 0px;margin-top: 0px;" data-width="97%"><span leaf=""><br/></span></section></section></section></section></section></section><p><br/></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">（1）降压药（部分钙拮抗剂）：</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">可能让血压过低引发头晕/站立不稳</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">硝苯地平（心痛定、拜新同等）</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">非洛地平（波依定等）</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">氨氯地平（部分复方含此成分，具个体差异、遵医嘱监测）</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">与西柚同服可能导致血药浓度升高、血压骤降，出现头晕、乏力、心悸等。</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">（2）降脂药（部分他汀）：</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">可能加重肌病/肝损伤风险</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">阿托伐他汀（立普妥）</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">辛伐他汀（舒降之）</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">洛伐他汀（美降之）</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">这类药本身就有肌肉疼痛、肝损伤的风险，和西柚同服后，药物浓度升高，风险会翻倍：可能出现肌肉酸痛、无力，甚至引发<span class="">横纹肌溶解症</span>，同时肝脏负担也会加重。可与医生讨论替代：普伐他汀、<span class="">瑞舒伐他汀</span>，这两种同类药物受代谢酶影响较小。</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">（3）部分抗过敏药（老药为主）：</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">可能明显加重嗜睡风险</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">特非那定（敏迪）</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">阿司咪唑（息斯敏，现已被更新药物替代，但仍需警惕旧药）</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">这类药本身就可能引起嗜睡，和西柚同服后，药效增强，嗜睡感会明显加重，开车、操作机器时极易发生危险。</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">（4）<span class="">免疫抑制剂</span>：</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">对浓度极其敏感，波动会带来严重后果</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">环孢素（新山地明等）</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;"><span class="">他克莫司</span>（普乐可复等）</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">与西柚同服可使药物在体内浓度显著变化，过高增加肾毒性/神经毒性，过低则免疫抑制不足。建议严格回避西柚及其制品。</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">（5）镇静催眠/麻醉前用药：</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">可能“睡过头”甚至呼吸抑制</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">咪达唑仑（短期助眠/麻醉前镇静）</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;"><span class="">地西泮</span>（安定，可能受影响）</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">与西柚同服会延缓代谢、延长作用时间，老年人或呼吸功能较差者风险更高。</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><br/></span></p><p><br/></p><section data-role="title" data-tools="135编辑器" data-id="164716" data-pm-slice="0 0 []"><section style="margin: 10px auto;display: flex;justify-content: center;"><section><section style="display: flex;justify-content: flex-end;height: 0px;transform: rotateZ(0deg);line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><br/></span></section><section style="display: flex;margin: 0 15px;"><section style="flex-shrink: 0;display: flex;align-items: flex-end;"><section style="width: 6px;height: 80%;border-left: 1px solid rgb(21, 84, 162);border-bottom: 1px solid rgb(21, 84, 162);border-top: 1px solid rgb(21, 84, 162);box-sizing: border-box;line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><br/></span></section></section><section style="width: 100%;max-width:100% !important;box-sizing:border-box;" data-width="100%"><section style="background-color: #faf7ef;padding: 6px 20px;box-sizing:border-box;"><section style="font-size: 18px;color: rgb(21, 84, 162);text-align: center;line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><strong data-brushtype="text"><span leaf="" data-pm-slice="1 1 "><span textstyle="" style="font-size: 16px; letter-spacing: 2px;">3个实用提醒帮你避开风险</span></span></strong></section></section><section style="height: 6px;width: 97%;border-right: 1px solid rgb(21, 84, 162);border-bottom: 1px solid rgb(21, 84, 162);box-sizing: border-box;line-height: 2em;margin-bottom: 0px;margin-top: 0px;" data-width="97%"><span leaf=""><br/></span></section></section></section></section></section></section><p><br/></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">吃药前先“两看”：</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">看说明书“药物相互作用”是否写明避免“西柚/葡萄柚”；再看药品通用名，是否属于前面提到的高风险药物类别。</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">不确定就“问”：</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">分不清自己吃到的是“西柚”还是“柚子”，或不清楚药物是否受影响，第一时间咨询医生/药师。</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">更安全的替代：</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">特别爱吃柚味但正在用高风险药（并非所有药都会受西柚影响，主要涉及强CYP3A4底物且首过代谢显著的口服药），如不确定，请咨询医生/药师。饮食上可选择橙、橘、苹果等通常更安全的水果。</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><br/></span></p><p><br/></p><section data-role="title" data-tools="135编辑器" data-id="164716" data-pm-slice="0 0 []"><section style="margin: 10px auto;display: flex;justify-content: center;"><section><section style="display: flex;justify-content: flex-end;height: 0px;transform: rotateZ(0deg);line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><br/></span></section><section style="display: flex;margin: 0 15px;"><section style="flex-shrink: 0;display: flex;align-items: flex-end;"><section style="width: 6px;height: 80%;border-left: 1px solid rgb(21, 84, 162);border-bottom: 1px solid rgb(21, 84, 162);border-top: 1px solid rgb(21, 84, 162);box-sizing: border-box;line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><br/></span></section></section><section style="width: 100%;max-width:100% !important;box-sizing:border-box;" data-width="100%"><section style="background-color: #faf7ef;padding: 6px 20px;box-sizing:border-box;"><section style="font-size: 18px;color: rgb(21, 84, 162);text-align: center;line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><strong data-brushtype="text"><span leaf="" data-pm-slice="1 1 "><span textstyle="" style="font-size: 16px; letter-spacing: 2px;">常见误区问答</span></span></strong></section></section><section style="height: 6px;width: 97%;border-right: 1px solid rgb(21, 84, 162);border-bottom: 1px solid rgb(21, 84, 162);box-sizing: border-box;line-height: 2em;margin-bottom: 0px;margin-top: 0px;" data-width="97%"><span leaf=""><br/></span></section></section></section></section></section></section><p><br/></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">1、西柚味饮料/果酱/酸奶算不算？</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">答：</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">多</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">数也算。</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">只要含有西柚提取物或汁液，都可能带来相互作用；加工并不一定能消除影响。</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">2、和西柚错开几小时就安全了吗？</span></span></p><p style="line-height: 2em;margin-bottom: 0px;margin-top: 0px;"><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">答：</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">未必。</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;">因其为“机制性抑制”，影响可持续24–72小时，</span></span><span leaf=""><span textstyle="" style="font-size: 16px;letter-spacing: 2px;font-weight: bold;">单纯错开时间并不可靠。</span></span></p><p>来源 央视财经</p><link rel="stylesheet" href="//www.fqlook.cn/source/plugin/wcn_editor/public/wcn_editor_fit.css?v134_cKz" id="wcn_editor_css"/> 注意食用注意事项 是该注意这些事， 注意药物与食物的配伍 福清融强贺医生 发表于 2025-11-2 21:21注意药物与食物的配伍
安全第一，不能大意， 注意饮食合理
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